PRF technology is based on the research of Dr. Joseph Choukroun. According to the research, a fibrin clot or PRF (Platelet Rich Fibrin), which contains the majority of the platelets and leukocytes in the blood, can be isolated from human blood by centrifugation under specific conditions.
When placed on human bone or soft tissue, the PRF clot will gradually start releasing growth factors (VEGF, PDGF, TGF Beta, Thrombospondin). This accelerates the growth and healing of bone and soft tissue, which is an important factor in oral surgery. The results are excellent and tissue growth is fast.
For instance, the properties of PRF can be used for accelerated healing after the following surgeries:
- Ridge augmentation
- Sinus lift
- Bone grafting and soft tissue grafting for dental implantation
- Tooth extraction (for filling the alveolus)
- Treatment of periodontitis
Recovery rate is directly liked to the overall health status of the patient, for example, the levels of vitamin D (normal 30–100 mg/mL) or blood haematocrit (normal 40–51%). Blood sugar level is also important (normal 3.30–5.90 mmol/L).
The preparation of a surgical treatment plan often requires the patient’s full blood analysis.
Blood tests can be performed at the clinic.
A-PRF (Advanced PRF) is a development of the PRF technology which results in a blood clot with an even greater concentration of platelets and leucocytes, making bone and soft tissue healing even faster.
I-PRF (Injectable PRF) is a fluid form of PRF that can be injected into tissues and thus used to accelerate blood circulation post-surgery. I-PRF also facilitates the binding of the artificial bone granules used in bone grafting.
For most surgeries, we take a few ampoules of venous blood from the patient to extract either A-PRF or I-PRF to ensure faster recovery of hard and soft tissues.
See also surgery.