PRF or Platelet Rich Fibrin

PRF technology relies on the concept based on scientific research of Dr Joseph Choukroun. Pursuant to that technology, under certain conditions it is possible to extract from human blood a fibrin clot or PRF (Platelet Rich Fibrin), which contains majority of platelets and leucocytes in person’s blood.

PRF clot, when placed on bone or soft tissue, will gradually excrete growth factors (VEGF, PDGF, TGF Beta, Thrombospondin). Thus results in quicker growth and healing of bone and soft tissue, which is a crucial factor for performing intraoral surgeries. The results are good and tissue growth is fast.

For example, the properties of PRF can be used to the advantage of quicker recovery in the healing phase after surgical procedures such as:
  • Bone ridge augmentation
  • Sinus lift
  • Growing bone and thickening or elongating the supporting soft tissue upon implantation
  • Filling the alveolus upon tooth extraction
  • Treatment of periodontitis

Recovery rate is directly associated with the overall status of health of the patient, including the level of vitamin D (norm. 30-100 mg/mL) or blood haematocrit (norm. 40-51 %). Blood sugar level is also important (norm. 3.30- 5.90 mmol/L).

Preparation of treatment plan concerning surgical treatment often requires patient’s full blood analysis. Blood sample can be taken at the clinic.

A-PRF (Advanced PRF) represents an advancement of PRF technology, resulting in blood clot with greater concentration of platelets and leucocytes, which makes bone and soft tissue healing even faster.

I-PRF (Injectable PRF) is PRF that is in a liquid state for a short time, and can be injected in the tissues and thus accelerate blood circulation for post-operative recovery. I-PRF also facilitates merging the artificial bone granules used for bone augmentation.

In most surgical treatments we take a few ampoules of venous blood from the patient, in order to extract A-PRF or I-PRF to ensure quicker recovery of hard and soft tissues.

See also Surgery

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